Pure EPA triglyceride (rTG)
Most omega-3 supplements are ethyl esters — cheaper to make, harder for an inflamed gut to absorb. EPAVANCE uses re-esterified triglyceride (rTG), the natural form your body recognises.
A medical food,
for the dietary management of IBD.
EPAVANCE delivers high strength EPA in triglyceride form — the only UK Food for Special Medical Purposes developed for the dietary management of inflammatory bowel disease.
The IBD Difference
Not a supplement.
Not a medicine.
Something purpose-built.
EPAVANCE is classified as a Food for Special Medical Purposes — a European regulatory category created specifically for products that manage the dietary needs of patients with a medical condition.
That means EPAVANCE is held to stricter standards than a supplement, and produced on the same lines as prescription medicines. Available and recommeneded to be used under medical supervision... no prescription required.

Our Heritage
Vance Medical Foods is a UK gastro-pharma company founded in 2014 by a team of clinicians and formulation scientists. We only make one thing — medical foods for gastrointestinal conditions — and we make them properly.
EPAVANCE is manufactured under pharmaceutical GMP, in a facility audited by the MHRA. Every batch is tested for EPA purity, oxidation, and heavy metals before release.
Our Product
A one-month supply of High Strength EPA in pure triglyceride form. Two soft-gel capsules daily, with food, for the dietary management of gastrointestinal inflammation associated with IBD.
The Science
Three formulation choices distinguish EPAVANCE from standard fish oil. Each one is deliberate, evidence-led, and documented in our clinician evidence pack.
Most omega-3 supplements are ethyl esters — cheaper to make, harder for an inflamed gut to absorb. EPAVANCE uses re-esterified triglyceride (rTG), the natural form your body recognises.
A standard fish-oil capsule contains validated high quality EPA. EPAVANCE delivers in a single soft-gel, so two capsules give a therapeutic dose without a stack of pills.
EPA plays a known role in the resolution phase of inflammation. EPAVANCE is the first UK FSMP developed specifically for the dietary management of IBD-associated inflammation.
Patient Voices
“My gastroenterologist mentioned EPAVANCE at my last review. I've been taking it alongside my biologics for four months — it's genuinely the first omega-3 I haven't given up on.”
“The regulatory category matters. When I recommend an FSMP to a patient I can be confident about purity, dosing and consistency in a way I can't with a supplement.”
“I like that the pack tells me exactly what's in it and that it's made with a pharma partner. Subscription arrives before I run out. Easy.”
Frequently Asked
No. EPAVANCE is a Food for Special Medical Purposes (FSMP), a European regulatory category for products that manage the dietary needs of patients with a medical condition. It is intended to be used under medical supervision, but does not require a prescription.
Take two soft-gel capsules daily with food, unless advised otherwise by your clinician. One pack (60 capsules) is a one-month supply at the standard maintenance dose. Some clinicians advise a higher loading dose in the first month — your HCP will guide you.
EPAVANCE is generally well-tolerated with common IBD therapies including 5-ASAs, immunomodulators and biologics. Always check with your gastroenterologist or GP before starting, particularly if you take anticoagulants.
The triglyceride (rTG) form is the natural molecular form of fish oil. Research shows it is more bioavailable than the ethyl ester form used in most supplements — especially relevant for people with inflamed or compromised gut absorption.
EPAVANCE is formulated in Cambridge, UK, manufactured under pharmaceutical GMP with our partner Sla Health, and dispatched from our facility in Leeds. Every batch is third-party tested for purity, oxidation, and heavy metals.
We currently ship within the UK with free tracked delivery. EU shipping is rolling out in 2026 — join the waitlist to be notified.
Two capsules, once a day. Delivered to your door, on your schedule. Skip or cancel anytime.